Antibacterial drugs

Azlocillin has an antimicrobial action similar to that of piperacillin. Its activity in vitro against Enterobacteriaceae is generally less than that of mezlocillin or piperacillin, but it has comparable activity to piperacillin against Pseudomonas aeruginosa.

Sultamicillin is given orally as tablets containing sultamicillin tosilate or as oral suspension containing sultamicillin. It is used in the treatment of infections where beta-lactamase-producing organisms might occur, including uncomplicated gonorrhoea, otitis media, and respiratory-tract and urinary-tract infections.

The name benzylpenicillin is commonly used to describe either benzylpenicillin potassium or benzylpenicillin sodium as these are the forms in which benzylpenicillin is used. Benzylpenicillin means either the potassium or sodium salt. The potassium salt of a substance produced by growing certain strains of Penicillium notatum or related organisms or obtained by any other means. A white or almost white crystalline powder.

Ampicillin is a beta-lactam antibiotic. It is bactericidal and has a similar mode of action to that of benzylpenicillin, but as an aminopenicillin with an amino group side-chain attached to the basic penicillin structure, ampicillin is better able to penetrate the outer membrane of some Gram-negative bacteria and has a broader spectrum of activity.