Mechanism of action
This product is an extremely effective anti-fungal agent widely used to treat jock itch, athlete’s foot and diverse yeast infections, as well as other common infections. Its active ingredients block the formation of the fungal cell membrane, preventing both normal development and division of pathogenic cells. The medication works by preventing the synthesis of ergosterol – a complex chemical compound crucial for the synthesis of fungal cell membranes. The drug inhibits lanosterol 14α-demethylase, which is a cytochrome P-450 dependent enzyme responsible for the metabolic transformation of lanosterol to ergosterol.
The health product helps in the treatment of fungal and yeast infections. It belongs to the group of remedies known as azole antifungals. The medication prevents the growth of various types of fungi by disrupting the production of the membranes that surround the fungal cells.
The effect of this medicine lasts for an average duration of 8 hours with the peak effect observed in 1–2 hours. This medicine is not recommended for use during pregnancy except for special cases when the pros outweigh all possible risks. The medication is not habit-forming; nonetheless, it should be taken in full compliance with the established schedule.
Indications
Both the appropriate dosage and the duration of therapy with the health product should be determined by by your healthcare provider depending on your age, weight, medical history, and current health status. The medication is used to treat the following infectious diseases:
- Ketzi Shampoo is used in the treatment of blastomycosis – a severe fungal infection that may affect the skin, bones, and joints. This disease is caused by the fungus Blastomyces dermatitidis.
- the Chromomycosis – a fungal infection that can affect both the skin and subcutaneous tissues caused by Fonsecaea pedrosoi/Phialophora verrucosa.
Obviously, the only available method of administration of Ketzi Shampoo is to apply it to the affected skin. However, it should be noted that the active ingredients of this medication are very impactful and widely used in treatment of various infectious diseases. For instance, these substances are used to cure respiratory infections including the following:
- Coccidioidomycosis – a fungal infection caused by Coccidioides. Unlike the previously mentioned fungal diseases, this infection can affect the lungs as well as other parts of the body.
- Histoplasmosis – a fungal infection caused by Histoplasma capsulatum. This infection mostly affects the respiratory system.
- Paracoccidioidomycosis – a fungal infection caused by Paracoccidioides brasiliensis. This infection affects the lungs.
Observed adverse reactions
The main negative effects of taking the medication include:
- Nausea
- Stomach pain
- Headache
- Diarrhea
Some rare side effects may include hair loss, depression, tingling sensations, and serious allergic reactions.
Interactions and precautions
You should inform your healthcare provider if you suffer from the following health disorders:
- Liver disease. Ketzi Shampoo should be administered with caution in individuals suffering from hepatic insufficiency. Suitable dosage adjustments and careful monitoring are necessary in such cases.
- Disorders of the cardiovascular system, especially health conditions associated with the QT prolongation syndrome. Ketzi Shampoo should be very carefully administered in patients with a history of heart conditions. Appropriate dosage adjustments and continuous monitoring are recommended in such cases.
- Kidney disease. Suitable adjustments of the recommended doses are required based on the degree of kidney failure.
Interaction with other drugs and food additives:
- Consumption of alcohol is not recommended when using this medicine. This combination may slightly increase the risk of dizziness and affect your ability to drive.
- You should inform your doctor about the therapy with of either of the drugs in order to make suitable dosage adjustments.
- Administration of Ketzi Shampoo while taking Cisapride is not recommended. Inform your doctor in case you are taking Cisapride so that a suitable replacement for Ketzi Shampoo could be prescribed.
- Administration of Ketzi Shampoo along with Erythromycin is not recommended. Inform your doctor about the therapy with either of these medicines. Your doctor might prescribe alternative medicines in order to minimize the potential side effects. Immediate medical help might be required if you feel dizzy, suffer from shortness of breath, and/or feel discomfort in the chest.
- Administration of Ketzi Shampoo along with Warfarin is recommended only after appropriate dose adjustments. Safety monitoring is necessary in such cases. Dangerous signs and symptoms like headache, blood urine, weakness, and/or bleeding should be reported immediately.
- Administration of Ketzi Shampoo with Atorvastatin is not recommended. Inform your doctor about the therapy with either of these medicines so that suitable replacements could be suggested. Symptoms like muscle pain and weakness coupled with fever, joint pain, and/or chills should be reported immediately.