Incidence/Prevalence in USA: Difficult to assess due to wide variability in false negative Papsmear reporting and uneven distribution of qualified colposcopy practitioners. Prevalence 3,600/100,000 at age 27-28. Predominant age: The median age for carcinoma in situ is 28 years. Earlier lesions can be expected at younger ages
What Causes Disease? Cellulitis around the eye in adult: Staphylococcus aureus most common, Streptococcus pyogenes, Streptococcus pneumonia, Mixed infection.
An acute, spreading infection of the dermis and subcutaneous tissue. Several entities are recognized: Treat 10-30 days. Guided by culture results whenever possible.
A mucocutaneous disorder caused by infection with various species of Candida. Candida is normally present, in very small amounts, in the oral cavity, gastrointestinal tract, and female genital tract. Genetics: Chronic mucocutaneous candidiasis is a heterogeneous clinical syndrome that usually presents in childhood and can have an autosomal recessive, dominant or sporadic mode of inheritance. Sera from HIV-infected patients with thrush have been screened for C. albicans genomic expression.
Candida albicans and related species cause a variety of infections. Cutaneous candidiasis syndromes include erosio interdigitalis blastomycetica, folliculitis, balanitis, intertrigo paronychia, onychomycosis, diaper rash, perianal candidiasis, and the syndromes of chronic mucocutaneous candidiasis. Mucous membrane infections include oral candidiasis (thrush), esophagitis, and vaginitis.
Systemic bacterial infection caused by Brucella species in infected animal products, or vaccine. Incubation period usually 5-60 days, but highly variable and may be several months.
Inflammation of the bronchioles, usually seen in young children, occasionally in high-risk adults. May be seasonal (winter and spring) and often occurs in epidemics.
Conditions that may lead to bronchiectasis include severe pneumonia (especially measles, pertussis, adenoviral infections in children), necrotizing infections due to Klebsiella, staphylococci, influenza virus, fungi, mycobacteria, mycoplasma, bronchial obstruction from any cause (foreign body, carcinoma, enlarged mediastinal lymph nodes.
Single or multiple abscesses within the brain, usually occurring secondary to a focus of infection outside the central nervous system. May mimic brain tumor but evolves more rapidly (days to a few weeks). It starts as a cerebritis, becomes necrotic, and subsequently becomes encapsulated.
An intoxication producing paralytic disease caused by neurotoxins of Clostridium botulism and is the most toxic substances known to science. The toxin prevents acetylcholine release at presynaptic membranes, blocking neuromuscular transmission in cholinergic nerve fibers. Electro my ogram (EMG) shows characteristic brief, low voltage compound motor-unit, small amplitude, overly abundant action potentials (BSAPs), incremental response to repetitive stimulation. Findings not definitive for botulism.