Author: Donna Brettler

Lymecycline is a tetracycline derivative with general properties similar to those of tetracycline. Although its absorption is not significantly affected by moderate amounts of milk, it is still affected by divalent and trivalent cations such as aluminium, bismuth, calcium, iron, magnesium, and zinc. Lymecycline is given orally and doses are expressed in terms of the equivalent amount of tetracycline base.

Loracarbef is an oral carbacephem antibiotic. The carbacephems are closely related to the cephalosporins, but replacement of the sulfur atom in the 7-aminocephalosporanic acid nucleus by a methylene group is said to enhance stability. It is used similarly to cefaclor in the treatment of susceptible infections of the respiratory and urinary tracts and of skin and soft tissue.

Lomefloxacin is a fluoroquinolone antibacterial with actions and uses similar to those of ciprofloxacin. It is given orally for the treatment of susceptible infections, including bronchitis due to Haemophilus influenzae or Moraxella catarrhalis (Branhamella catarrhalis), and urinary-tract infections.

Kanamycin is an aminoglycoside antibacterial with actions similar to those of gentamicin. It has been used in the treatment of susceptible Gram-negative and staphylococcal infections, including gonorrhoea and neonatal gonococcal eye infections, although its use has declined in many centres because of the development of resistance.

Cefalexin is a first-generation cephalosporin antibacterial. It is given orally for the treatment of susceptible infections including those of the respiratory and urinary tracts and of the skin.

Cefadroxil is a first-generation cephalosporin antibacterial that is the parahydroxy derivative of cefalexin, and is used similarly in the treatment of mild to moderate susceptible infections.

Linezolid is an oxazolidinone antibacterial with activity against a range of aerobic Gram-positive bacteria including vancomycin-resistant enterococci and meticillin-resistant Staphylococcus aureus. It is less active against Gram-negative bacteria, but has some in-vitro activity against Haemophilus influenzae, Legionella spp., Moraxella catarrhalis (Branhamella catarrhalis), Neisseria gonorrhoeae, and Pasteurella spp.

Levofloxacin is generally considered to be about twice as active as ofloxacin, the racemic substance. Levofloxacin has a broad spectrum of activity which includes Gram-positive bacteria.