Important Information about Zovirax (Acyclovir) Cream
- This medicine is used to treat recurrent herpes labialis (cold sores) caused by the herpes simplex virus.
- It is indicated for use in adults and adolescents aged 12 years and older.
- For best results, apply the cream five times a day for four days, starting at the first sign of an outbreak (such as tingling or itching).
- If the cold sore has not healed after four days, treatment can be continued for up to ten days.
- Zovirax cream should not be applied to the eyes or inside the mouth. It is contraindicated in individuals with known hypersensitivity to Acyclovir or its components.
Do Not Use…
- During pregnancy or while breastfeeding without consulting your healthcare provider.
Do Not Give…
- To children under 12 years of age.
Please read the rest of the leaflet before you use this medicine. It includes other information that may be especially important to you.
- Keep this leaflet, as you may need to reread it.
- Ask your pharmacist if you need more information or advice.
- If any of the side effects become serious or if you notice any not listed in this leaflet, please tell your doctor or pharmacist.
What Is the Medicine for
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Zovirax cream is indicated for treating recurrent herpes labialis (cold sores) caused by the herpes simplex virus. It contains Acyclovir, which helps reduce the severity and duration of symptoms when applied early in an outbreak.
Before You Use Acyclovir Tablets
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Do not use the medicine if you or your child
- Have an allergy to acyclovir, valacyclovir, or any component of the formulation.
- Is under 12 years old.
Pregnant or Breastfeeding…
Consult your doctor or pharmacist for advice before using this medicine if you are pregnant, might be pregnant, or are breastfeeding. Acyclovir is classified as a pregnancy category B drug by the US FDA, indicating that animal studies have shown low risk. Still, there are no adequate and well-controlled studies in pregnant women.
Important information about some of the ingredients
This product contains propylene glycol and cetostearyl alcohol, which may cause local skin reactions such as stinging or burning sensations. If you have a known intolerance to these substances, contact your doctor before using this medicinal product.
How to Use
Apply a sufficient quantity of Zovirax cream to cover the affected area thoroughly.
Adults and Adolescents (12 years and older)
Apply the cream five times a day for four days, starting at the first sign of a cold sore (such as tingling or itching).
Children under 12 years
Do not use Zovirax (Acyclovir) cream unless directed by your doctor.
Follow-up Dose:
If the cold sore has not healed after four days, treatment can be continued for up to ten days. Consult your doctor if symptoms persist beyond this period.
If You Take too Many
Due to limited absorption, topical overdosage is unlikely, but if excessive amounts are applied, wash the area with soap and water. If irritation occurs, consult your healthcare provider.
Missed Dose
If you forget to apply a dose, do so as soon as you remember. However, if it is nearly time for your next application, skip the missed dose and continue with your regular schedule.
Possible Side Effects
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Like all medicines, Zovirax (Acyclovir) cream can have side effects, although they don’t affect everyone.
Possible side effects are:
- Mild pain, burning, or stinging at the application site.
- Dry, flaky skin or cracked lips.
- Itching or redness in the treated area.
Rarely:
- Severe allergic reactions such as hives, swelling of the face, lips, or throat, and difficulty breathing.
- There are signs of kidney injury, such as swelling in the ankles or feet, blood in the urine, or painful urination.
- Unusual mood changes or confusion.
If you notice these or any other side effects not included above, stop using the cream and tell your doctor or pharmacist. They will advise you on what to do.
Storing
Before purchasing Acyclovir, you must read how to store
- Keep it out of the reach and sight of children.
- Do not store above 25°C.
- Store in the original package.
- Do not use it after the expiration date shown on the carton. The expiry date refers to the last day of that month.
- Medicine should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of any unused medicine. These measures will help to protect the environment.
Further Information
The active ingredient in Zovirax cream is:
-
Acyclovir 5% w/w (50 mg per gram of cream).
The other ingredients are cetostearyl alcohol, mineral oil, poloxamer 407, propylene glycol, sodium lauryl sulfate, water, and white petrolatum.
What Zovirax Cream Looks Like
Zovirax cream is a smooth white to off-white cream. It is available in tubes containing 2 grams or 5 grams of the product, with a beveled edge. The cream is also available in carton blister packs, either as a one-person treatment containing 2 tablets or as a family pack containing 8 tablets.
Marketing Authorization Holder
Zovirax is marketed by GlaxoSmithKline UK.
Manufacturer
Zovirax cream is manufactured by GlaxoSmithKline, Mississauga, Ontario, Canada.
Health and Hygiene Information
What Are Cold Sores?
Cold sores are small, fluid-filled blisters that typically appear on or around the lips. They are caused by the herpes simplex virus (HSV) and can be triggered by stress, illness, or sun exposure. Cold sores are widespread and can affect individuals of all ages.
Where Do Cold Sores Come from?
Cold sores are highly contagious and can be spread through close personal contact or by sharing items like utensils, towels, or lip balm. Once infected, the virus remains dormant in the body and can reactivate periodically, leading to recurrent outbreaks.
Hygiene Rules to Prevent Cold Sores
- Avoid close contact with others during an outbreak.
- Do not share personal items that may have come into contact with the cold sore.
- Wash hands frequently, especially after touching the affected area.
- Keep the affected area clean and avoid picking at blisters to prevent secondary infections.
Following these hygiene practices can help reduce the risk of spreading the virus to others and minimize the likelihood of recurrent outbreaks.