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Amoxil (Amoxicillin)

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What Amoxil (Amoxicillin) 500mg Is

Amoxil Vials for Injection 500 mg and 1 g (called Amoxil in this leaflet) are antibiotics. The vials contain a medicine called amoxicillin. This belongs to a group of medicines called ‘penicillins’.

What Amoxil (Amoxicillin) 500mg Is used for

Before buy Amoxicillin online, read information about the drug

Amoxil is used to treat infections in different parts of the body caused by bacteria. It is also used to stop infections when you have a tooth removed or other surgery. Amoxil Vials for Injection are usually used for urgent treatment of severe infection or if patients cannot take Amoxil by mouth.

Amoxil Vials for Injection

Do not have Amoxil Amoxil (Amoxicillin) 500mg if you:

  • are allergic (hypersensitive) to amoxicillin or penicillin
  • have ever had an allergic (hypersensitive) reaction to any antibiotic. This can include a skin rash or swelling of the face or neck.

Do not have Amoxil if any of the above apply. If you are not sure, talk to your doctor, pharmacist or nurse before having Amoxil.

Take special care with Amoxicillin (Amoxil) 500mg

Check with your doctor, pharmacist or nurse before having this medicine if you:

  1. have glandular fever
  2. are being treated for kidney problems
  3. are not passing water regularly.

If you are not sure if any of the above apply to you, talk to your doctor, pharmacist or nurse before you have Amoxil.

Having urine or blood tests

If you are having tests on your water (urine glucose tests) or blood tests for liver function, let the doctor or nurse know that you are on Amoxil. This is because Amoxil can affect the results of these tests.

Taking other medicines Amoxicillin (Amoxil) 500mg

Please tell your doctor, pharmacist or nurse if you are taking or have recently taken any other medicines. This includes medicines that can be bought without a prescription and herbal medicines. This is because Amoxil can affect the way some other medicines work. Also some other medicines can affect the way Amoxil works.

If you are taking allopurinol (used for gout) with Amoxil, it may be more likely that you’ll have an allergic skin reaction.

If you are taking probenecid (used for gout), your doctor may decide to adjust your dose of Amoxil.

If medicines to help stop blood clots (such as warfarin) are taken with Amoxil then extra blood tests may be needed.

Amoxil may stop the contraceptive pill working. You will need to use extra contraceptive precautions, such as using a condom. If you need any advice, talk to your doctor, pharmacist or nurse.

Pregnancy and breast-feeding

Ask your doctor, pharmacist or nurse for advice before taking any medicine if you think you might be or if you are pregnant or if you are breast-feeding.

Important information about one of the ingredients of Amoxicillin (Amoxil) 500mg

Each vial of Amoxil Vials for Injection 500 mg contains 38 mg of sodium.

Each vial of Amoxil Vials for Injection 1 g contains 76 mg of sodium.

This should be considered if you are on a controlled sodium diet.

You will never give yourself this medicine. A qualified person, like a doctor or a nurse, will give you this medicine.

Amoxil will be given as an injection or an infusion into a vein (intravenously) or muscle (intramuscularly).

Your doctor will decide how much you need each day and how often the injections should be given.

Make sure you drink plenty of fluids while having Amoxil.

To treat infections

The usual doses are as follows.

Children up to 10 years of age

Most infections: 50 mg to 100 mg for every kilogram of body weight in divided doses throughout the day.

To prevent infections after surgery: the dose will vary according to the type of surgery. The doctor, pharmacist or nurse will advise you exactly how much medicine and when you will need it.

  • For children aged 5 to 10 years, the dose is usually half the adult dose to prevent infections after surgery, see below.
  • For children to 5 years, the dose is usually one-quarter of the adult dose to prevent infections after surgery, see below.

Adults, elderly patients and children over 10 years of age

Most infections: 500 mg every 8 hours into muscle. This might be given by slow injection into a vein if this is more convenient.

Severe infections: 1 g every 6 hours into a vein.

To prevent infections after surgery: the dose will vary according to the type of surgery. The doctor, pharmacist or nurse will advise you exactly how much medicine and when you will need it.

You may need to have 1 x 1 g injection into a vein or muscle before surgery, sometimes with other medicines. This may be followed by further Amoxil doses (oral or injection) later in a 24 hour period or for several days.

Kidney problems

If you have kidney problems the dose might be lower than the usual dose.

If more Amoxil is given to you than recommended

It is unlikely you will be given too much, but if you think you have been given too much Amoxil, tell your doctor, pharmacist or nurse immediately. Signs might be an upset stomach (feeling sick, being sick or diarrhoea) or crystals in the urine, which may be seen as cloudy urine or problems passing urine.

If you think you have missed an injection of Amoxil

Speak to your doctor, pharmacist or nurse.

How long will you need to take Amoxil for?

You will not normally be given Amoxil for more than 2 weeks without the doctor reviewing your treatment.

Thrush (a yeast infection of moist areas of the body) may develop if Amoxil is used for a long time. If this occurs and you have been taking Amoxil for longer than recommended, tell your doctor, pharmacist or nurse.

If you have any further questions about how this product is given, ask your doctor, pharmacist or nurse.

Possible side effects Amoxicillin (Amoxil) 500mg

Like all medicines, Amoxil can cause side effects, although not everybody gets them. The following side effects may happen with this medicine.

Tell your doctor or nurse straight away if you notice any of the following serious side effects – you may need urgent medical treatment:

The following are very rare (affects less than 1 in 10,000 people)

  • allergic reactions, the signs may include: skin itching or rash, swelling of the face, lips, tongue, body or breathing difficulties. These can be serious and occasionally deaths have occurred
  • rash or pinpoint flat red round spots under the skin surface or bruising of the skin. This is due to inflammation of blood vessel walls due to an allergic reaction. It can be associated with joint pain (arthritis) and kidney problems
  • a delayed allergic reaction can occur usually 7 to 12 days after having Amoxil, some signs include: rashes, fever, joint pains and enlargement of the lymph nodes especially under the arms
  • a skin reaction known as ‘erythema multiforme’ where you may develop: itchy reddish purple patches on the skin especially on the palms of the hands or soles of the feet, ‘hive-like’ raised swollen areas on the skin, tender areas on the surfaces of the mouth, eyes and private parts. You may have a fever and be very tired
  • other severe skin reactions can include: changes in skin colour, bumps under the skin, blistering, pustules, peeling, redness, pain, itching, scaling. These may be associated with fever, headaches and body aches
  • high temperature (fever), chills, a sore throat or other signs of an infection, or if you bruise easily. These may be signs of a problem with your blood cells
  • inflammation of the large bowel (colon) with diarrhoea sometimes containing blood, pain and fever
  • serious liver side effects may occur which are often reversible. They are mainly associated with people having treatment over a long period, males and the elderly. You must tell your doctor or nurse urgently if you get:
    • severe diarrhoea with bleeding
    • blisters, redness or bruising of the skin
    • darker urine or paler stools
    • yellowing of the skin or the whites of the eyes (jaundice). See also anaemia below which might result in jaundice.

These can happen when having the medicine or for up to several weeks after.

If any of the above happen to you talk to your doctor or nurse straight away as your medicine should be stopped.

Sometimes you may get less severe skin reactions such as:

  • a mildly itchy rash (round, pink-red patches), ‘hive-like’ swollen areas on forearms, legs, palms, hands or feet. This is uncommon (affects less than 1 in 100 people).

If you have any of these talk to your doctor or nurse as Amoxil will need to be stopped. The other possible side effects are:

Common (affects less than 1 in 10 people)

  1. skin rash
  2. feeling sick (nausea)
  3. diarrhoea.

Uncommon (affects less than 1 in 100 people)

  1. being sick (vomiting).

Very rare (affects less than 1 in 10,000 people)

  1. thrush (a yeast infection of the vagina, mouth or skin folds), you can get treatment for thrush from your doctor, pharmacist or nurse
  2. kidney problems
  3. fits (convulsions), seen in patients on high doses or with kidney problems
  4. dizziness
  5. hyperactivity
  6. crystals in the urine, which may be seen as cloudy urine, or difficulty or discomfort in passing urine. Make sure you drink plenty of fluids to reduce the chance of these symptoms
  7. an excessive breakdown of red blood cells causing a form of anaemia. Signs include: tiredness, headaches, shortness of breath, dizziness, looking pale and yellowing of the skin and the whites of the eyes
  8. the blood may take longer to clot than it normally would. You may notice this if you have a nosebleed or cut yourself.

If any of the side effects gets serious, or if you have any side effects not listed in this leaflet, please tell your doctor, pharmacist or nurse.

Amoxil Vials for Injection are for use in hospital only and the expiry date and storage instructions stated on the label are for the doctor, pharmacist or nurse’s information. The doctor, pharmacist or nurse will make up your medicine. When administered directly into a muscle or a vein, it should be used immediately following reconstitution (usually this process takes about 5 minutes). (If Amoxil is being administered by slow infusion this takes about half to one hour.)

What Amoxicillin (Amoxil) 500mg contains

Amoxil Vials for Injection are available in 2 strengths.

Amoxil Vials for Injection 500 mg contains amoxicillin 500 mg.

Amoxil Vials for Injection 1 g each contain amoxicillin 1,000 mg.

There are no other ingredients. However, for information about sodium in Amoxil, please see section 2 Important information about one of the ingredients of Amoxil.

The doctor, nurse or pharmacist will make up the injection before use using an appropriate fluid (such as Water for Injections or an injection/infusion fluid).

What Amoxicillin (Amoxil) 500mg looks like and contents of the pack

Amoxil is supplied as a clear glass vial of sterile powder for making up as an injection. The vial has a rubber bung and an aluminium foil overseal. The vials are packed in cartons of 10.

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