Co-amoxiclav (Amoxicillin/Clavulanic Acid)
What Co-amoxiclav is and what it is used for
Read indications for use if you want to order Co-Amoxiclav online
Co-amoxiclav is an antibiotic and works by killing bacteria that cause infections. It contains two different medicines called amoxicillin and clavulanic acid. Amoxicillin belongs to a group of medicines called “penicillins” that can sometimes be stopped from working (made inactive). The other active component (clavulanic acid) stops this from happening.
Co-amoxiclav is used in adults and children to treat the following infections:
- middle ear and sinus infections
- respiratory tract infections
- urinary tract infections
- skin and soft tissue infections including dental infections
- bone and j oint infections.
Before you give Co-amoxiclav
Before buy Co-Amoxiclav online, read information about the drug
Do not give your child Co-amoxiclav:
- if they are allergic (hypersensitive) to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of Co-amoxiclav (listed in section 6)
- if they have ever had a severe allergic (hypersensitive) reaction to any other antibiotic. This can include a skin rash or swelling of the face or neck
- if they have ever had liver problems or jaundice (yellowing of the skin) when taking an antibiotic.
Do not give Co-amoxiclav to your child if any of the above apply to your child. If you are not sure, talk to your doctor or pharmacist before giving Co-amoxiclav.
Take special care with Co-amoxiclav:
Check with their doctor or pharmacist before giving your child this medicine if they:
- have glandular fever
- are being treated for liver or kidney problems
- are not passing water regularly.
If you are not sure if any of the above apply to your child, talk to their doctor or pharmacist before giving Co-amoxiclav.
In some cases, your doctor may investigate the type of bacteria that is causing your child’s infection. Depending on the results, your child may be given a different strength of Co-amoxiclav or a different medicine.
Conditions you need to look out for Co-amoxiclav can make some existing conditions worse, or cause serious side effects. These include allergic reactions, convulsions (fits) and inflammation of the large intestine. You must look out for certain symptoms while your child is taking Co-amoxiclav, to reduce the risk of any problems. See ‘ Conditions you need to look out for’ in Section 4.
Blood and urine tests
If your child is having blood tests (such as red blood cell status tests or liver function tests) or urine tests (for glucose), let the doctor or nurse know that they are taking Co-amoxiclav. This is because Co-amoxiclav can affect the results of these types of tests.
Using other medicines
Please tell your doctor or pharmacist if your child is taking or has recently taken any other medicines. This includes medicines that can be bought without a prescription and herbal medicines.
- If your child is taking allopurinol (used for gout) with Co-amoxiclav, it may be more likely that they will have an allergic skin reaction.
- If your child is taking probenecid (used for gout), your doctor may decide to adjust your dose of Co-amoxiclav.
- If medicines to help stop blood clots (such as warfarin) are taken with Co-amoxiclav then extra blood tests may be needed.
Co-amoxiclav can affect how methotrexate (a medicine used to treat cancer or rheumatic diseases) works.
Pregnancy and breast-feeding:
If your child who is about to take this medicine is pregnant or breast-feeding, please tell your doctor or pharmacist.
Ask your doctor or pharmacist for advice before taking any medicine.
Important information about some of the ingredients of Co-amoxiclav
Co-amoxiclav contains aspartame (E951) which is a source of phenylalanine. This may be harmful for children born with a condition called ‘phenylketonuria’.
Co-amoxiclav contains glucose and sorbitol. If you have been told by your doctor that you are intolerant to some sugars, contact your doctor before taking this medicine.
How to give Co-amoxiclav
When you buy cheap Co-Amoxiclav you must know how to use it
Always give Co-amoxiclav exactly as your doctor has told you. You should check with your doctor or pharmacist, if you are not sure.
Adults and children weighing 40 kg and over
This suspension is not usually recommended for adults and children weighing 40 kg and over. Ask your doctor or pharmacist for advice.
Children weighing less than 40 kg
All doses are worked out depending on the child’s body weight in kilograms.
Your doctor will advise you how much Co-amoxiclav you should give to your baby or child.
You may be provided with a plastic measuring spoon or syringe doser. You should use this to give the correct dose to your baby or child.
- Usual dose – 25 mg/3.6 mg to 45 mg/6.4 mg for each kilogram of body weight a day, given in two divided doses.
- Higher dose – up to 70 mg/10 mg for each kilogram of body weight a day, given in two divided doses.
Patients with kidney and liver problems
If your child has kidney problems the dose might be changed. A different strength or a different medicine may be chosen by your doctor.
If your child has liver problems they may have more frequent blood tests to check how their liver is working.
How to give Co-amoxiclav
Always shake the bottle well before each dose
Give at the start of a meal or slightly before
Space the doses evenly during the day, at least 4 hours apart. Do not take 2 doses in 1 hour.
Do not give your child Co-amoxiclav for more than 2 weeks. If your child still feels unwell they should go back to see the doctor.
If you give more Co-amoxiclav than you should
If you give your child too much Co-amoxiclav, signs might include an upset stomach (feeling sick, being sick or diarrhoea) or convulsions. Talk to their doctor as soon as possible. Take the medicine bottle to show the doctor.
If you forget to give Co-amoxiclav
If you forget to give your child a dose, give it as soon as you remember. You should not give your child the next dose too soon, but wait about 4 hours before giving the next dose.
If your child stops taking Co-amoxiclav
Keep giving your child Co-amoxiclav until the treatment is finished, even if they feel better. Your child needs every dose to help fight the infection. If some bacteria survive they can cause the infection to come back.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Possible side effects
Read side effects if you want cheap Co-Amoxiclav no prescription
Like all medicines, Co-amoxiclav can cause side effects, although not everybody gets them.
Conditions you need to look out for
Allergic reactions:
- skin rash
- inflammation of blood vessels (vasculitis) which may be visible as red or purple raised spots on the skin, but can affect other parts of the body
- fever, joint pain, swollen glands in the neck, armpit or groin
- swelling, sometimes of the face or mouth (angioedema), causing difficulty in breathing
- collapse.
Contact a doctor immediately if your child gets any of these symptoms. Stop taking Co-amoxiclav.
Inflammation of large intestine
Inflammation of the large intestine, causing watery diarrhoea usually with blood and mucus, stomach pain and/or fever.
Contact your doctor as soon as possible for advice if your child gets these symptoms.
Very common side effects (These may affect more than 1 in 10 people)
- diarrhoea (in adults).
Common side effects (These may affect up to 1 in 10 people)
- thrush (candida – a yeast infection of the vagina, mouth or skin folds)
- feeling sick (nausea), especially when taking high doses. If affected take Co-amoxiclav before food.
- vomiting
- diarrhoea (in children).
Uncommon side effects (These may affect up to 1 in 100 people)
- skin rash, itching
- raised itchy rash {hives)
- indigestion
- dizziness
- headache.
Uncommon side effects that may show up in your blood tests:
- increase in some substances {enzymes) produced by the liver
Rare side effects (These may affect up to 1 in 1000 people)
- skin rash, which may blister, and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge – erythema multiforme)
if you notice any of these symptoms contact a doctor urgently.
Rare side effects that may show up in your blood tests:
- low number of cells involved in blood clotting
- low number of white blood cells
Other side effects
Other side effects have occurred in a very small number of people but their exact frequency is unknown.
- Allergic reactions (see above)
- Inflammation of the large intestine (see above)
- Serious skin reactions:
- a widespread rash with blisters and peeling skin, particularly around the mouth, nose eyes and genitals {Stevens-Johnson syndrome), and a more severe form, causing extensive peeling of the skin (more than 30% of the body surface – toxic epidermal necrolysis) – widespread red skin rash with small pus-containing blisters (bullous exfoliative dermatitis)
- a red, scaly rash with bumps under the skin and blisters (exanthemouspustulosis) Contact a doctor immediately if your child gets any of these symptoms.
- inflammation of the liver {hepatitis)
- jaundice, caused by increases in the blood of bilirubin (a substance produced in the liver) which may make your child’s skin and whites of the eyes appear yellow
- inflammation of tubes in the kidney
- blood takes longer to clot
- hyperactivity
- convulsions (in people taking high doses of Co-amoxiclav or who have kidney problems)
- black tongue which looks hairy
- stained teeth (in children), usually removed by brushing
Side effects that may show up in blood or urine tests:
- severe reduction in the number of white blood cells
- low number of red blood cells (haemolytic anaemia)
- crystals in urine.
If your child gets side effects, tell your doctor of pharmacist if any of the side effects become severe or troublesome, or if you notice any side effects not listed in this leaflet.
How to store Co-Amoxiclav
Before purchase Co-Amoxiclav, you must read how to store
Keep out of the reach and sight of children.
The reconstituted suspension should be stored in a refrigerator (2°-8° C) and used within 7 days. Keep in the original container. Keep the container tightly closed.
Do not use Co-amoxiclav after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.
Medicines should be not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Further information
What Co-amoxiclav contains
The active substances are amoxicillin and clavulanic acid.
1 ml reconstituted suspension (corresponding to 0.160 g powder) contains:
Amoxicillin trihydrate corresponding to 80 mg amoxicillin.
Potassium clavulanate corresponding to 11.4 mg clavulanic acid
Other ingredients are: Citric acid, Trisodium citrate, Aspartame (E951), Talc, Guar galactomannan, Silicon dioxide, Lemon flavouring (natural flavouring materials, nature-identical flavouring materials,dextrose, maltodextrin, butylated hydroxyanisole E320, sorbitol syrup E420, Acacia gum E414); Peach-apricot flavouring, (natural flavouring materials, nature-identical flavouring materials, maltodextrin, butylated hydroxyanisole E320, sorbitol syrup E420, Acacia gum E414); Orange flavouring (nature-identical flavouring materials, artificial flavouring substances, maltodextrin, alpha-tocopherol E 307).
What Co-amoxiclav looks like and contents of the pack
The primary packaging materials consists of
Amber glass bottle (type III), 60 ml, 120 ml respectively 150 ml.
Screw closure with sealing membrane graduated syringe (5 ml) for 60 ml bottles (for pack sizes of 35 ml, 50 ml, 60 ml suspension)
measuring spoon (5 ml) for 120 ml bottles (for pack sizes of 70 ml, 75 ml, 100 ml suspension) and 150 ml bottles (for a pack size of 140 ml suspension)
Original packs for preparing of 35, 50, 60, 70, 75, 100 and 140 ml suspension.
Not all pack sizes may be marketed.
| This medicinal product is authorised in the Member States of the EEA under the following names: | |
| Austria | Co-Amoxiclav Aurobindo 500 mg / 125 mg Filmtabletten |
| Belgium | Amoxicilline / Clavulanic acid Aurobindo 500 mg / 125 mg comprimés pellicules |
| Bulgaria | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg филмирани таблетки |
| Czech Republic | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg potahované tablety |
| Denmark | Amoxiclllln / Clavulansyre Aurobindo |
| Estonia | Amoxicillin / Clavulanic acid Aurobindo |
| Finland | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg tabletti, kalvopäällysteinen |
| Germany | Amoxi-Clavulan Aurobindo 500 mg / 125 mg Filmtabletten |
| Greece | Amoxicillin+Clavulanic acid Aurobindo (500+125) mg επικαλυμμένο με λεπτό υμένιο δισκία |
| Hungary | Amoxicillin / Klavulánsav Aurobindo 500 mg / 125 mg filmtabletta |
| Ireland | Co-Amoxiclav Aurobindo 500 mg / 125 mg film-coated tablets |
| Latvia | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg apvalkotās tablets |
| Lithuania | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg plevele dengtos tabletas |
| Luxembourg | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg comprimés pelliculés |
| Netherlands | Amoxicllllne / Clavulaanzuur Aurobindo 500 mg / 125 mg, filmomhulde tabletten |
| Poland | Amoxicillin / Clavulanic acid Aurobindo |
| Portugal | Amoxicilina + Ácido Clavulânico Aurobindo |
| Romania | Amoxicilină / Acid clavulanic Aurobindo 500mg / 125mg, comprimate fílmate |
| Slovak Republic | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg fllmom obalené tablety |
| Slovenia | Amoksicilin / Klavulanska kislina Aurobindo 500 mg / 125 mg filmsko oblozena tableta |
| Spain | AMOXICILINA / ACIDO CLAVULÂNICO AUROBINDO 500 / 125 mg comprimidos recubiertos con película |
| Sweden | Amoxicillin / Clavulanic acid Aurobindo 500 mg / 125 mg fllmdragerade tabletter |
| United Kingdom | Co-amoxiclav 500 mg / 125 mg film-coated tablets |