Surgical Prophylaxis

The traditional classification system developed by the National Research Council  stratifying surgical procedures by infection risk is reproduced in Table NRC Wound Classification, Risk of SSI, and Indication for Antibiotics. The National Research Council wound classification for a specific procedure is determined intraoperatively.

Skin and Soft Tissue Infections

Impetigo is a superficial skin infection that is seen most commonly in children. It is highly communicable and spreads through close contact. Most cases are caused by S. pyogenes, but S. aureus either alone or in combination with S. pyogenes has emerged as a principal cause of impetigo.

Trichomoniasis

The spectrum of sexually transmitted diseases includes the classic venereal diseases – gonorrhea, syphilis, chancroid, lymphogranuloma venereum, and granuloma inguinale – as well as a variety of other pathogens known to be spread by sexual contact (Table Sexually Transmitted Diseases). Common clinical syndromes associated with sexually transmitted diseases are listed in Table Selected Syndromes Associated with Common Sexually Transmitted Pathogens.

Genital herpes: diagnosis, treatment

The term herpes is used to describe two distinct but antigenically related serotypes of herpes simplex virus. Herpes simplex virus type 1 (Herpes Simplex Virus-1) is most commonly associated with oropharyngeal disease; type 2 (Herpes Simplex Virus-2) is most closely associated with genital disease.

Sepsis and Septic Shock

Lipid A is a part of the endotoxin molecule that is highly immunoreactive and is responsible for most of the toxic effects. Endotoxin first associates with a protein called lipopolysaccharide-binding protein in plasma.

Respiratory Tract Infections, Upper

The goals of treatment include reduction in signs and symptoms, eradication of infection, and prevention of complications. Avoidance of unnecessary antibiotic use is another goal in view of S. pneumonia. dClindamycin is only recommended in cases of documented S. pneumoniae. It is not effective against H. influenzae or M. catarrhalis.